modafinil will lower the extent or impact of mavacamten by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.
modafinil will boost the amount or result of pantoprazole by affecting hepatic enzyme CYP2C19 metabolism. Small/Significance Unfamiliar. Net impact on pantoprazole actions mysterious due to opposing outcomes of CYP450 enzymes; check
This medicine is accessible only with the doctor's prescription. This item is obtainable in the following dosage kinds:
Never end utilizing your CPAP equipment throughout slumber Except your medical doctor lets you know to. The mixture of cure with CPAP and Provigil could be essential to greatest treat your affliction.
On top of that, if getting modafinil every single day, the concentrations in the bloodstream can start to Develop up with time.
If the two medicines are prescribed with each other, your medical doctor may change the dose or how often you utilize a single or both with the medicines.
[18] Intense renal and/or hepatic impairment is thought to result in noticeably greater continuous-condition drug concentrations. Dose reduction is suggested in patients with critical hepatic impairment.
Avoid or substitute An additional drug for these medicines when feasible. Assess for lack of therapeutic result if medication must be coadministered. Regulate dose according to prescribing data if necessary.
phenytoin will lower the extent or impact of modafinil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
modafinil will improve the amount or impact of rabeprazole by affecting hepatic enzyme CYP2C19 metabolism. Small/Significance Unfamiliar. Internet impact on pantoprazole steps not known as a result of opposing results of CYP450 enzymes; keep an eye on
dizziness; sleepiness; tiredness; irritability; falls; nausea and vomiting; body weight acquire; vertigo (perception of spinning); issues strolling Usually; issues with muscle mass coordination; headache; bruising; abdominal ache; stress and anxiety more information FYCOMPA is really a controlled compound (CIII) because it might be abused or produce drug dependence.
modafinil will lessen the level or result of cocaine topical by influencing hepatic enzyme CYP2B6 metabolism. Small/Importance Unknown.
modafinil will decrease the extent or result of norgestrel by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Observe Closely. Average CYP3A4 inducers may perhaps lower progestin focus; look at usage of added barrier methods
Additionally, numerous intentional acute overdoses transpired; The 2 major being 4500 mg and 4000 mg taken by two subjects participating in foreign depression scientific studies. None of those review topics expert any unanticipated or life-threatening effects. Adverse reactions that were reported at these doses integrated excitation or agitation, insomnia, and slight or moderate elevations in hemodynamic parameters.